Yildirim Cinar, An excellent. Mete Senyol, Kamber Duman, Bloodstream viscosity and blood pressure levels: character out-of heat and you will hyperglycemia, American Diary away from Blood pressure levels, Volume step step step one4, Situation 5, , Profiles 433–438,
Conceptual
We planned a study to research the relations among blood pressure (BP), viscosity, and temperature in healthy subjects and among BP, viscosity, and glucose in diabetics. With simple random sampling method, 53 healthy and 29 diabetes mellitus (DM) type II subjects were selected. Parameters were determined with capillary viscometer and glucometer at 22°C, 36.5°C, and 39.5°C in healthy subjects, and at 22°C on diabetic patients during OGTT with 75 g of glucose. Statistical evaluations of the data were made with regression analysis, Student t test, Spearman’s correlation, and analysis of variance. When temperature decreased from 36.5°C to 22°C, blood viscosity increased %. This increase resulted in a % decrease in blood flow rate. According to the Hagen-Poiseuille equation, the required BP increase for compensation of the resulting tissue ischemia was %. Also, a % decrease in erythrocyte deformability and % increase in plasma viscosity were seen. When temperature increased from 36.5° to 39.5°C, blood viscosity decreased %. This caused % decrease in blood flow rate, and % decrease in BP, according to the equation. Erythrocyte deformability increase of 9.92% and plasma viscosity decrease of 4.99% arose from the temperature rise. There is a correlation between total data for temperatures and viscosities (r = ?0.84, P < .001). When the mean value of blood glucose increased from 100 to 400 mg/dL, viscosity increased 25% (r = 0.59, P = .002). In this state, blood flow rate decrease was 20% and BP increase for physiological compensation was 25%. Consequently, temperature, glucose and viscosity levels of blood are important factors for BP. Am J Hypertens 2001;–438 © 2001 American Journal of Hypertension, Ltd.
The aim of our data should be to research the relationships certainly one of temperature, sugar concentration, and viscosity regarding bloodstream and plasma, in order to calculate the consequences towards the blood pressure (BP) considering Hagen-Poiseuille’s hydrodynamics formula.
If the human circulatory system is considered as a closed system, hemodynamic equilibrium can be determined according to Poiseuille’s equation through the pressure, viscosity, flow rate, velocity of blood, and vessel diameter. Viscosity can be defined as the resistance of fluids against flow. The resistance for blood circulation includes friction between the blood elements and between the vessel lumen and blood. To make a fluid flow, the application of energy is required. Therefore, the energy of the circulatory system is spent in correlation with the viscosity level of blood. Energy forms of the circulatory system are BP and blood flow velocity. The velocity (v) and pressure of blood flow can be determined with Poiseuille’s equation as v = 1/4?L (F1 ? F2) (a 2 ? r https://datingranking.net/android-hookup-apps/ 2 ), and also BP rate (Q) can be expressed from the above equation as Q = ?a 4 /8 ?L (F1 ? F2), where ? is the viscosity of the fluid, F1 and F2 are the initial and the final cross sectional pressures of blood, L is the length, a is the radius of vessel, and r is the distance from the center of the vessel for a flowing particle. 1, 2 Thus, to keep the equilibrium of the equation constant in the circulatory system, BP will increase when viscosity increases.
Bloodstream viscosity and blood pressure levels: character from heat and you may hyperglycemia
It has been found one to between % and % values out-of hematocrit, all 11% rise in hematocrit develops blood viscosity by the 20%. Inside county, considering Poiseuille’s picture, blood circulation price minimizes of the %, which may cause tissue ischemia. To store the fresh new circulatory program inside harmony (that’s, staying the fresh move price sufficient and you will preventing tissue ischemia), a good 20% boost in BP or cuatro.66% vasodilation is required. 3 However, the human being circulatory system is maybe not an accurate closed program, because the bloodstream viscosity shall be altered on assimilation away from dinner or medicines. 4–8 On the other hand, the results away from dietary fat as well as some medicines on bloodstream viscosity and you can hemodynamics such as for instance BP have been claimed. Due to the fact atherosclerotic boats usually do not dilate good enough since a reaction to vasodilator drugs, it’s been suggested that increased bloodstream viscosity can simply feel paid having an effective BP upsurge in particularly situations. 9–a dozen In addition to, the matchmaking among BP, headache, coagulation, blood supply velocity, and blood viscosity was demonstrated through the prices regarding hemodynamics. 13, 14
